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Persistent hyperparathyroidism as a risk factor for long-term graft failure: The need to discuss indication for parathyroidectomy

Surgery Jan 30, 2018

Araujo MJCLN, et al. - As per current guidelines, performing parathyroidectomy is recommended if serum parathormone is persistently elevated 1 year after kidney transplant (KTx), because persistent hyperparathyroidism (pHPT) has been recently associated with poor graft outcomes. Researchers here assess if patients with pHPT and adequate renal function are at risk for long-term graft failure. After a successful KTx, having pHPT increases the long-term risk of death-censored graft failure. Findings thus underscore the necessity for better recognition and management of chronic kidney disease (CKD)-mineral and bone disorders (MBD) before and during the first year after KTx.
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