Luckett R, Painter H, Hacker MR, et al. - Researchers conducted a prospective cohort study among women living with HIV with the aim to evaluate 1-year outcomes of cervical cancer screening and treatment using primary high-risk human papillomavirus (HPV) testing in these women. Cervical cancer screening with high-risk HPV testing and triage evaluation were performed at baseline and 1-year follow-up among participants. Screening of 300 women was done at baseline, follow-up was attended by 237 of these women (79%). After one round of high-risk HPV-based screening and treatment, women living with HIV showed high incidence of high-risk HPV and high-grade cervical dysplasia which raises concern about the rate of progression of high-risk HPV infection to dysplasia. Persistent disease is common. Findings overall justify practicing caution in spacing cervical cancer screening intervals using high-risk HPV testing in women living with HIV.