Perioperative statin use may reduce postoperative arrhythmia rates after total joint arthroplasty
Journal of Arthroplasty Jun 03, 2021
Bonano JC, Aratani A, Sambare T, et al. - Researchers investigated if the incidence of 90-day postoperative arrhythmias in patients undergoing primary total joint arthroplasty (TJA) can be lowered by using statins perioperatively. A single-center retrospective cohort study was performed including 231 primary TJA patients (109 hips, 122 knees) receiving Simvastatin 80 mg daily during their hospitalization. Researchers matched this cohort with 966 primary TJA patients (387 hips and 579 knees) that were not administered Simvastatin. Per outcomes, use of a perioperative statin was linked with about 10-fold reduction in the relative risk of developing a postoperative arrhythmia within 90-days of arthroplasty and an absolute risk reduction of 3.6%.
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