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Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications and thromboembolic events: A Dutch multicenter matched-cohort clinical study

Surgery Sep 28, 2020

Jonker PKC, van der Plas WY, Steinkamp PJ, et al. - Researchers sought to perform a direct comparison of SARS-CoV-2 positive patients with a SARS-CoV-2 negative control group undergoing an operative intervention during the current pandemic and determined the difference in morbidity and mortality between both patient categories. Inclusion was performed of 161 SARS-CoV-2 positive and 342 control SARS-CoV-2 negative patients. After propensity score-matching, they compared 123 patients (median 70 years of age [IQR 59-77] and 55% male) in the SARS-CoV-2 positive group with 196 patients in the matched control group (median 69 years (IQR 58 – 75] and 53% male). Outcomes revealed greater odds of 30-day mortality, pulmonary complications, and thromboembolic events among patients diagnosed with perioperative SARS-CoV-2. In view of these findings, they support to postpone elective surgery as well as selected emergency cases.  

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