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Perioperative radiotherapy is an independent risk factor for major LARS: A cross-sectional observational study

International Journal of Colorectal Disease Jul 24, 2018

Nuytens F, et al. - A cross-sectional observational study was conducted to ascertain the prevalence of low anterior resection syndrome (LARS) in the institution and to detect possible risk factors for LARS, as well as evaluated which of the LARS symptoms were considered most disabling by patients and regardless of whether there was an adaptation of the LARS score over time. A prospective database of 100 patients who had total or partial mesorectal excision between January 2009 and September 2014 was included. Researchers reported that perioperative radiotherapy was an independent risk factor for major LARS. In the majority of patients with major LARS, fragmentation was considered the most disabling complaint and there was no significant adaptation of the LARS score over time.
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