Perioperative hemodynamics and outcomes of patients on metyrosine undergoing resection of pheochromocytoma or paraganglioma
International Journal of Surgery Aug 17, 2017
Butz JJ, et al. – This study aimed to describe outcomes of patients with metyrosine (MET) pretreatment for abdominal surgical resection of pheochromocytoma or paraganglioma (PCC/PGL) compared with patients who had phenoxybenzamine (PBZ) pretreatment. In the PCC/PGL patients treated with MET + PBZ, researchers observed large hemodynamic oscillations. These patients indicated a wider range of intraoperative blood pressure variations than PBZ–only patients. MET + PBZ and PBZ–only groups were similar regarding postoperative comorbid outcomes.
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