Tseng JH, et al. - In patients undergoing primary debulking surgery (PDS) for advanced ovarian cancer, researchers performed this retrospective study to evaluate the effect of epidural anesthesia on patient survival. Among consecutive patients with stage IIIB-IV epithelial ovarian, fallopian tube, or peritoneal carcinoma who had PDS from January 2005- December 2013, the main focus was on progression-free survival (PFS) and overall survival (OS) in relation to epidural use. Higher stage disease, carcinomatosis, and bulky upper abdominal disease was more likely to be seen among the 435 patients who received an epidural out of a total of 648 patients. For the epidural vs non-epidural groups, median PFS was 20.8 months and 13.9 months, respectively, and median OS was 62.4 months and 41.9 months, respectively. Findings demonstrated an independent association of perioperative epidural use with improved PFS and OS in these patients.