Jones JH, et al. - A systematic review was performed to evaluate the effect of perioperative dexmedetomidine for outpatient cataract surgery. Researchers carried out to searche Cochrane, Embase, and PubMed for randomized clinical trials evaluating the use of dexmedetomidine in adult patients undergoing outpatient, or ambulatory, cataract surgery with sedation and topical or peribulbar block. There were 914 patients who were included in the study. This study indicates better analgesia, higher patient satisfaction, and decreased IOP with dexmedetomidine for outpatient cataract surgery when compared to traditional sedatives, hypnotics, and opioids. These advantages of dexmedetomidine, nevertheless, must be weighed against relative cardiovascular depression and delayed PACU discharge or recovery times. Thus, for outpatient cataract surgery, the usefulness of dexmedetomidine should be considered on a patient-by-patient basis.