Perineural and intravenous dexamethasone and dexmedetomidine: Network meta‐analysis of adjunctive effects on supraclavicular brachial plexus block
Anaesthesia Nov 26, 2020
Sehmbi H, Brull R, Ceballos KR, et al. - Via performing a network meta‐analysis, researchers here compared and ranked the effects of perineural and intravenous dexamethasone and dexmedetomidine as supraclavicular block adjuncts. Inclusion was performed of 100 trials (5,728 patients). Findings suggest that irrespective of route employed, dexamethasone as an adjunct led to prolongation in the durations of sensory and analgesic blockade to a greater extent than dexmedetomidine. No clinically important differences were identified in block characteristics between perineural and intravenous dexamethasone. There appeared no effect of intravenous dexmedetomidine on block characteristics.
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