Calvo VE, Melguizo SC, Abascal-Saiz A, et al. - In this multicentre, prospective, observational study, researchers sought to assess the perinatal and maternal outcomes of pregnancies in SARS-CoV-2 infected women, comparing spontaneous and in vitro fertilization (IVF) pregnancies (with either own or donor oocytes). One thousand three hundred forty-seven SARS-CoV-2 positive pregnant women registered consecutively between February 26 and November 5, 2020. Patient´s information was obtained from their medical records, and multivariable regression analyses were conducted, controlling for maternal age and the clinical presentation of infection. There were 74 (5.5%) women in the IVF group, while there were 1,275 (94.5%) women in the spontaneous group. A high rate of operative delivery has been observed in SARS-CoV-2 infected women, particularly in IVF pregnancies; the method of conception has no effect on foetal or maternal outcomes, except for pre-eclampsia.