Rusconi F, Gagliardi L, Gori E, et al. - From the Piccolipiù birth cohort (Italy), a total of 2314 mother-child pairs were investigated for the links between maternal mental health in pregnancy and post-delivery and subsequent offspring wheezing and infections. For maternal mental health evaluation, the General Health Questionnaire-12 was used. In this study, the development of both wheezing and infections was reported in relation to maternal mental health problems extending from pregnancy to the first year following delivery. Since infections frequently trigger wheezing, a likely common biologic mechanism could be increased infection susceptibility. It was corroborated that early-life exposures play a significant role in childhood health.