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Pericoronary adipose tissue and quantitative global non-calcified plaque characteristics from CT angiography do not differ in matched South Asian, East Asian and European-Origin Caucasian patients with stable chest pain

European Journal of Radiology Feb 14, 2020

Goeller M, Ihdayhid AR, Cadet S, et al. - Researchers tried to find out the association between plaque characteristics and pericoronary adipose tissue (PCAT) attenuation and to evaluate gender and ethnic differences in PCAT attenuation using a matched cohort of South Asian (SA), East Asians (EA), and Caucasians. This study included a total of 300 symptomatic individuals who underwent CTA were matched for age, gender, BMI and diabetes (100 in each ethnic group). Semi-automated software was applied to measure the total volumes and burden of non-calcified plaque (NCP), low-density non-calcified plaque (LD-NCP) and calcified plaque (CP) in the blinded core-lab analysis. PCAT CT attenuation associated most with its surrounded NCP features additional highlighting its role as surrogate measure of coronary inflammation. The causes of increased cardiac mortality in South Asians need further studies, as coronary plaque burden and PCAT attenuation did not differ between ethnic groups
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