Peri‐operative and longterm outcomes of utilizing donation after circulatory death liver grafts with macrosteatosis: A multicenter analysis
American Journal of Transplantation Mar 31, 2020
Croome KP, Mathur AK, Mao S, et al. - Given the potentially additive risk from using donor livers that are both steatotic and from a donation after circulatory death (DCD) donor, researchers here sought to retrieve data on the outcome of DCD liver transplantation (LT) utilizing livers with macrosteatosis. They assessed 714 DCD LT performed at Mayo Clinic‐Florida, Mayo Clinic‐Arizona and Mayo Clinic‐Rochester from 1999‐2019. Classification of recipients of DCD LT into 3 groups was done: those with Moderate Macrosteatosis (30‐60%), Mild Macrosteatosis (5‐30%) and No Steatosis. Outcomes suggest the possible utility of DCD donors with mild macrosteatosis < 30% with no increase in peri‐operative complications and similar patient and graft survival compared with DCD donors with no steatosis. Higher rates of postreperfusion syndrome, primary non‐function, postreperfusion cardiac arrest, early allograft dysfunction and acute kidney injury should be anticipated when DCD donors with moderate macrosteatosis are utilized
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