Yamamoto K, Shiomi H, Morimoto T, et al. - Since there is a paucity of real-world data on the comparative long-term clinical results between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for unprotected left main coronary artery disease (ULMCAD) in new-generation drug-eluting stents era, therefore, researchers investigated this subject by analyzing 855 patients with ULMCAD (PCI: N = 383 [45%], and CABG: N = 472 [55%]) who were selected from the CREDO-Kyoto PCI/CABG registry Cohort-3. All-cause death was the primary outcome measure. Findings revealed no excess long-term death risk of PCI vs CABG, while for myocardial infarction and any coronary revascularization, the excess risks of PCI vs CABG were identified to be significant in this study populace reflecting real-world clinical practice in Japan.