Potts J, Mohamed MO, Mattei JCL, et al. - Among patients undergoing percutaneous coronary intervention (PCI) in the United States, researchers assessed in-hospital clinical outcomes in correlation with a current leukemia diagnosis. They used the National Inpatient Sample. They subclassified the patients as those having acute myeloid leukemia (AML) or chronic myeloid leukemia and acute lymphoid leukemia or chronic lymphoid leukemia. Significantly increased odds of in-hospital mortality and bleeding were observed in correlation with a leukemia diagnosis, after multivariable adjustment, whereas a fivefold increase of in-hospital mortality was seen in patients with AML. Overall, an increased risk of procedure-related complications post-PCI was observed in patients with current diagnosis of leukemia. In order to reduce procedural complications and enhance outcomes in this high-risk cohort, there is a requirement for a multidisciplinary approach among interventional cardiologists, oncologists, and hematologists.