Alexopoulos A, et al. - This research incorporated an analysis of the epidemiology, clinical manifestations, laboratory findings, course, and outcome of Greek children presenting with the vasculitic rash. The findings reported were as follows: Henoch-Schonlein purpura was the most common vasculitis presenting with skin rash in children. Hypersensitivity vasculitis appeared in older children more often than other types of vasculitis. The urticarial vasculitis lesions could present as a sign of severe underlying disease, which necessitated a comprehensive examination of these patients. Regardless of relapses, the overall prognosis of patients with pediatric skin vasculitides was found to be good, the exception of those with the urticarial vasculitis type.

Methods

• Data was extracted through a standardized form from children who were admitted into the department between 2003 and 2013, with the provisional diagnosis of vasculitis of the skin.
• The enrollment comprised of 95 children (58 boys, 37 girls) with a mean age of 5.9 years.

Results

• 76 out of 95 (80%) children were diagnosed with Henoch-Schonlein purpura, 10/95 (10.5%) with hypersensitivity vasculitis, 6/95 (6.3%) with urticarial vasculitis, and 3/95 (3.1%) with acute hemorrhagic edema of infancy.
• The mean age of the children was 5.7 years for Henoch-Schonlein purpura, 9 years for hypersensitivity vasculitis, 5.1 years for urticarial vasculitis, and 0.5 years for acute hemorrhagic edema of infancy.