Pediatric anesthesia severe adverse events leading to anesthetic morbidity and mortality in a tertiary care center in a low- and middle-income country: A 25-year audit
Anesthesia & Analgesia Dec 23, 2020
Khoso N, Ghaffar WB, Abassi S, et al. - Because assessment of adverse events, including morbidity and mortality (M&M), aids in the detection of subgroups of children at risk as well as in altering clinical practice, and since data available from low- and middle-income countries are scanty, therefore, researchers estimated the proportion of children with various severe adverse events in the perioperative period extending to 48 hours as well as reported the clinical situations and reasons for those events. For this purpose, the M&M database of the Department of Anesthesiology between 1992 and 2016 was examined. Findings revealed an uncommon occurrence of adverse events, and the most frequent (33%) were respiratory complications. A higher risk for perioperative cardiac arrest was noted in infants, specifically those with congenital heart disease, but this link was not tested statistically. Death within 48 hours occurred in 28% of the patients who developed events. A reduction in perioperative cardiac arrests was reported in relation to increased access to anesthesia drugs and practice improvements.
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