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Pediatric acute respiratory distress syndrome associated with human metapneumovirus and respiratory syncytial virus

Pediatric Pulmonology Jun 01, 2018

Ravindranath TM, et al. - In this retrospective, observational study, the researchers intended to investigate the incidence, risk factors, clinical course, and outcome of ARDS in children with HMP and RSV. Study participants were patients <18 years old with HMP or RSV detected from nasopharyngeal specimens by commercial reverse transcriptase polymerase chain reaction assay admitted to a study site. Using recently developed Pediatric ARDS (PARDS) criteria, the incidence of ARDS within 1 week following the detection of HMP or RSV was described. It was observed in the findings that about 1/3 of children with HMP or RSV and acute (or acute-on-chronic) respiratory failure developed PARDS. It was noted that children with either virus and a neurologic comorbidity or an increased PIM 3 probability of mortality were at increased risk for PARDS.
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