Peak inspiratory flow measured at different inhaler resistances in patients with asthma
The Journal of Allergy and Clinical Immunology: In Practice Nov 03, 2020
Haughney J, Lee AJ, McKnight E, et al. - This study was sought to ascertain the proportion of patients with asthma who could generate the correct peak inspiratory flow rate (PIFR) at different inhaler resistance settings. Researchers checked patients' PIFR at resistance settings matching their current preventer inhaler device, at R5 (high-resistance dry powder inhaler [DPI]) and at R0 (low resistance, pressurized metered-dose inhaler [pMDI]) during a UK asthma review service. The analysis enrolled a sum of 994 adults (females 64.3%), of whom 90.4% currently used a preventer inhaler (71.5% pMDI). This research findings illustrate that most individuals with asthma can achieve adequate inspiratory flow to activate high-resistance DPIs, whereas approximately a third of patients breathe in too fast to achieve recommended inspiratory flows for correct pMDI use, including one-fifth of patients who currently use a pMDI preventer.
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