Swärd P, Tofik R, Bakoush O, et al. - Researchers examined the link between urinary IgM, albuminuria, and vascular parameters reflecting arterial structure as well as function. Participants were selected from the Malmö Offspring study cohort, and involved 1,531 offspring (children and grand-children) to first-generation individuals that took part in the Malmö Diet Cancer-Cardiovascular Arm study cohort. As per the results, increased urinary IgM (U-IgM) excretion and low-grade albuminuria were found to be related to adverse vascular parameters in young to middle-aged, mostly healthy persons in this study. Experts inferred that subclinical peripheral atherosclerosis may be reflected by increased U-IgM excretion, whereas increased urinary albumin excretion was shown to be related to a broad range of cardiovascular abnormalities. This may reflect different pathophysiological mechanisms.