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Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance

European Heart Journal Feb 22, 2021

Kotecha T, Knight DS, Razvi Y, et al. - Multi-parametric cardiovascular magnetic resonance (CMR) was performed to evaluate myocardial injury in recovered COVID-19 patients. Researchers included a total of 148 individuals (64 ± 12 years, 70% male) with severe COVID-19 infection [all requiring hospital admission, 48 (32%) requiring ventilatory support] and troponin elevation discharged from six hospitals had undergone convalescent CMR (including adenosine stress perfusion if indicated) at median 68 days. The data suggested that myocarditis-like injury can be encountered, with a limited extent and minimal functional consequence during convalescence after severe COVID-19 infection with troponin elevation. There is evidence of possible ongoing localized inflammation in a proportion of patients. A quarter of individuals had ischaemic heart disease, of which two-thirds had no previous history. If these observed findings represent pre-existing clinically silent disease or de novo COVID-19-related variations remain undetermined. They did not detect diffuse edema or fibrosis.

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