Creo A, et al. - Using a retrospective cohort, researchers analyzed the patterns of thyroid dysfunction induced by amiodarone in pediatric patients. They analyzed 527 pediatric patients who were treated with amiodarone between 1997 and 2017. “Short term” and “long term” amiodarone therapy was defined as therapy lasting for 3-30 days and >30 days, respectively. In this study, 27 neonates, 25 infants, 27 young children and 71 children were examined. Compared to older children, more thyroid dysfunction with higher degrees of thyroid-stimulating hormone (TSH) elevation was observed in neonates and infants receiving amiodarone therapy. Even with short-term exposure, increases in TSH occurred early. More rigorous pediatric-specific thyroid monitoring guidelines are required.