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Patterns in adolescent cannabis use predict the onset and symptom structure of schizophrenia-spectrum disorder

Schizophrenia Research Feb 10, 2018

Shahzade C, et al. - Researchers aimed to investigate adolescent cannabis use as a risk factor for schizophrenia spectrum disorder (SSD). They also examined the motives for early cannabis use and resulting usage patterns alongside clinical measures of SSD onset and symptomatology. In this work, factor-analysis of reported motives for initiating cannabis use yielded 4 groups; sedation, stimulation, social pressure, and recreation. They observed that the onset of SSD was hastened and the severity was amplified with adolescent cannabis use. For identifying at risk individuals, predicting the onset and severity of SSD, and potentially mitigating the associated psychiatric impairments, they proposed a model.
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