Vakharia RM, Sodhi N, Anis HK, et al. - Researchers sought to explore whether individuals with cannabis use disorder undergoing primary total knee arthroplasty (TKA) have higher rates of venous thromboemboli (VTEs); readmissions; and costs. They distinguished study group individuals undergoing primary TKA from a large, nationwide database. They eliminated individuals who had a history of VTEs, deep vein thromboses (DVTs), pulmonary emboli (PEs), and coagulopathies before their TKA. They matched study group individuals to controls in a 1:4 ratio by age, sex, a comorbidity index, and medical comorbidities. They examined a sum of 18,388 individuals (cannabis = 3680; controls = 14,708). Outcomes examined incorporated rates of 90-day VTEs, DVTs, and PEs, in addition to 90-day readmissions and costs. They obtained that, compared with a matched cohort, individuals who have a cannabis use disorder have higher rates of thromboembolic complications, readmission rates, and costs following primary TKA.