Leitao MM, Zhou QC, Gomez-Hidalgo NR, et al. - This is the first study contrasting the prevalence of patient-reported lower-extremity lymphedema (LEL) with sentinel lymph node (SLN) mapping vs comprehensive lymph node dissection (LND) for the surgical management of newly diagnosed endometrial carcinoma. Six hundred twenty-three responded to the survey and 599 were evaluable of 1,275 potential candidates. Findings suggested an independent association of SLN mapping with a significantly lower prevalence of patient-reported LEL. An increased prevalence of patient-reported LEL was associated with high BMI and adjuvant external-beam radiation therapy.