Fotheringham J, Vilar E, Bansal T, et al. - For longer (4.5hr) and more frequent (4 sessions per week) hemodialysis (HD) regimens, their predicted acceptance is substantially greater than their employment in current clinical practice.

• This study involved 183 prevalent in-center hemodialysis patients (mean 4.7 years on dialysis, mean age of 63.7 years).

• Of them, 38.3% (70/183) always preferred to remain on regimens of 3 sessions per week with session duration of 4 hours rather than opting for longer (4.5hr) or more frequent hemodialysis (4 sessions per week) regimens.

• Depicted links of increasing survival and quality of life, decreased requirement for fluid restriction, and preventing additional access complications were all significantly related to opting longer or more frequent treatment regimes.

• Following factors were linked with preference for 4 sessions per week: younger age, fatigue, previous experience of vascular access complications, absence of heart failure, and shorter travel time to dialysis centers.

• The fully adjusted model showed 27.1% and 34.3% would prefer longer regimens delivered 3 times per week and 4hrs 4 times per week, respectively.

• For younger fatigued patients living near their unit, analogous estimates were 23.5% and 62.5%, respectively.