The African COVID-19 Critical Care Outcomes Study (ACCCOS) Investigators, et al. - Researchers conducted the African COVID-19 Critical Care Outcomes Study (ACCCOS) with the aim to determine the resources, comorbidities, and critical care interventions that are linked with mortality in African patients with COVID-19 who are critically ill. In this multicenter, prospective, observational cohort study in adults (aged 18 years or older), they included adults (aged 18 years or older) with suspected or confirmed COVID-19 infection who were referred to intensive care or high-care units in 64 hospitals in ten African countries (ie, Egypt, Ethiopia, Ghana, Kenya, Libya, Malawi, Mozambique, Niger, Nigeria, and South Africa). Of 6,779 patients referred to critical care, 3,752 (55·3%) patients were admitted and 3,140 (83·7%) patients took part in this study. Outcomes revealed higher mortality in critically ill patients with COVID-19 in African countries relative to that reported in studies done in Asia, Europe, North America, and South America. Insufficient critical care resources, as well as the comorbidities of HIV/AIDS, diabetes, chronic liver disease, and kidney disease, and severity of organ dysfunction at admission were identified to be linked with the increased mortality.