Hogan J, et al. - Researchers analyzed patient survival on dialysis and 10-year graft survival in all children starting renal replacement therapy (RRT) before 24 months of age between 1992 and 2012 in France, using the national Renal Epidemiology and Information Network (REIN) registry, to ultimately help clinicians and parents regarding deciding on RRT initiation and transplantation management. The only factor that was found to be related to both an increased risk of death on dialysis and a decreased probability of being transplanted was suffering from extrarenal comorbidities. The 10-year graft survival was 74%. This study confirmed the good outcome of children starting RRT before 2 years of age and offered data on the optimal morphological and immunological matching.