Sykes P, et al. - In this prospective multi-center study in eight participating centers in Australia and New Zealand, researchers present the interim findings of an audit of the outcomes of sentinel node (SN) biopsy done in place of groin node dissection in routine clinical practice in 130 women with early stage vulvar cancer. The eligibility for participants included presence of squamous cell carcinomas clinically restricted to the vulva <4 cm in diameter. According to the methods published by the GROINSS-V collaboration, SN procedures and pathological evaluations were carried out. Findings highlighted the feasibility of performing SN biopsy in routine clinical practice. However, groin recurrence could be related to undetected metastases in a removed SN. It appeared important to strictly adhere to the pathology protocol to ensure patient safety when utilizing sentinel lymph node technique in vulvar cancer.