Parenteral drug use as the main barrier to hepatitis C treatment uptake in HIV-infected patients
HIV Medicine Apr 26, 2019
Rivero-Juarez A, et al. - Researchers sought patient factors that are correlated to not being treated for hepatitis C virus (HCV) infection in HIV-coinfected patients. In this prospective longitudinal study, the study population included HIV-infected patients with active chronic HCV infection (n=3,075) from the HERACLES cohort (NCT02511496). They separated the population into patients who were getting HCV treatment and those who were not. Significant independent risk factors associated with low odds of direct-acting antiviral implementation were age < 50 years, absence of or minimal liver fibrosis, being treatment-naïve, HCV genotype 3 infection, being a person who injects drugs using opioid substitutive therapy (OST-PWID), and or recent PWID.
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