Rios P, et al. - The link between parental smoking and alcohol consumption and the risk of neuroblastoma (NB) was investigated in a pooled analysis of two French national population-based case-control studies including mothers of 357 NB cases and 1,783 controls from general population, frequency matched by age and sex. The participants were inquired about demographic, socioeconomic and perinatal characteristics, maternal reproductive story, and life-style and childhood environment. Pooled odds ratios and 95% confidence intervals were estimated using unconditional logistic regression. They also performed a meta-analysis of their findings with those of previous studies. There was no association between paternal smoking in the year before child's birth and NB, as independent exposure. However, a stronger link was reported when both parents reported having smoked during pregnancy. Maternal alcohol intake during pregnancy was not related to NB. Overall, some evidence was found for a link between maternal smoking during pregnancy and NB.