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Pain associated with cervical priming for first-trimester surgical abortion: A randomized controlled trial

Obstetrics and Gynecology May 28, 2021

Hamdaoui N, Cardinale C, Fabre C, et al. - Via performing a randomized, single-blind, two-center study, the effect of cervical priming with mifepristone was compared with that of misoprostol on pain perception during surgical induced abortion under paracervical block. Of 314 eligible women, 110 were randomized (55 in each group). Outcomes suggest higher effectiveness of cervical priming with mifepristone for surgical induced abortion under paracervical block up to 14 weeks of gestation than misoprostol in reducing pain perception.

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