Li WF, et al. - Researchers assessed oxygen therapy as a management option for patients with acute myocardial infarction (AMI), focusing on its effectiveness and safety, in this meta-analysis of randomized controlled trials (RCTs). They analyzed data from six RCTs that used oxygen therapy for patients with suspected or confirmed AMI < 24 hours of symptoms onset. These studies were identified from MEDLINE, CINAHL, EMBASE, databases, as well as the Cochrane Central Register of Controlled Trials, searched from January 1, 1967, through December 31, 2017. They performed meta-analysis, excluding hyperbaric and aqueous oxygen therapy trials. According to findings, there was no benefit of oxygen inhalation in patients with AMI with normal oxygen saturation.