Juan YH, Huang PC, Lin G, et al. - This study was undertaken to correlate the differences in myocardial oxygenation status among patients with ischemic HF, non-ischemic heart failure (HF) and controls. Researchers prospectively included a total of 60 participants, comprising 20 HF patients with left ventricular ejection fraction (LVEF) ≥ 50% as the improved ejection fraction group, 20 H F patients with ejection fraction <50% as the reduced ejection fraction (HFREF) group, and 20 controls. They compared T2* values across the study groups, and correlated with LVEF, myocardial scar distribution and quantity. The evidence exhibited that in chronic heart failure patients, oxygen-sensitive T2* measurements indicated association with LVEF and ischemic etiology, while the ischemic HFREF patients seemed to be more vulnerable to myocardial oxygen reduction than other groups. Via myocardial oxygenation , T2* measurements may be clinically useful in monitoring heart failure and lay the foundation for further research in prognostication heart failure recovery.