Hajjar I, et al. - In this study, researchers sought to determine the link between aminothiol markers of oxidative stress (OS) and inflammation in cognitive decline, specifically in the executive cognitive domain which is highly susceptible to cardiovascular risk factors and is an important predictor of cognitive disability. They found that in a healthy population, increased OS reflected by decreased glutathione was associated with a decline in executive function. In contrast, no link was apparent between inflammation and cognitive decline. As per the observations, OS may be an earlier biomarker that precedes the inflammatory phase of executive decline with aging.