van der Hel OL, Timmermans M, van Altena AM, et al. - Researchers conducted a population-based study in the Netherlands to describe trends in the incidence, treatment, and survival of women with ovarian tumors that have non-epithelial histology, including germ cell tumors (GCTs), sex cord-stromal tumors (SCSTs) and sarcomas. From the Netherlands Cancer Registry, they identified a total of 1,258 non-epithelial ovarian tumors comprising 752 GCTs (60%), 341 SCSTs (27%) and 165 sarcomas (13%). This study suggests rarity of malignant GCTs and SCSTs; their incidence has not significantly changed over recent decades. Observations revealed the European age-standardized incidence rate (ESR) of 0.4 per 100,000 persons per year for GCTs, 0.2 for SCSTs and 0.1 for sarcomas. Surgical resection was performed in approximately 97% of patients for the primary tumor, systemic treatment was provided in 31% and radiotherapy was provided in 3%. Improvement in 5-year overall survival was observed for all histologic subtypes from the late 1980s to 2015: for GCTs overall survival rose from 73% to 88%, for SCSTs from 64% to 81% and for sarcomas from 20% to 29%.