Cai HQ, et al. - The relationship between minichromosome maintenance protein (MCM) mRNA expression and clinical parameters in three hundred twenty-five gliomas were analyzed. The authors discovered that MCM6 presented high expression and was associated with poor survival. Findings revealed that patients with IDH1 mutation and low MCM6 expression displayed the longest survival, whereas those with high MCM6 expression and wild-type IDH1 presented the shortest. They suggested that MCM6 is a novel potential biomarker for predicting poor prognosis of the patients with glioma.