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Overexpression of SSH1 in gastric adenocarcinoma and its correlation with clinicopathological features

Journal of Gastrointestinal Oncology Jul 23, 2018

Daryabari SS, et al. - Researchers compared the expression level of slingshot diphosphatase 1 (SSH1) genes between tumor and corresponding adjacent non- tumor gastric tissues and healthy tissue. mRNA of 40 gastric adenocarcinoma and corresponding adjacent non- tumor gastric tissues and 15 healthy biopsy samples were assessed. Significant increases in the expression of this gene in gastric cancer tissue vs adjacent non- tumor gastric tissue samples and normal tissue was seen. For gastric cancer, this gene could also be used as a biomarker. For SSH1, the biomarker index was obtained as 0.89.

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