Overall survival of black and white men with metastatic castration-resistant prostate cancer treated with docetaxel
Journal of Clinical Oncology Feb 13, 2019
Halabi S, et al. - Researchers undertook this investigation to assess the overall survival (OS) in black vs white men with metastatic castration-resistant prostate cancer (mCRPC) treated in phase 3 clinical trials with docetaxel plus prednisone (DP) or a DP-containing regimen. They combined individual participant data from 8,820 men with mCRPC randomized in nine phase 3 trials to DP or a DP-containing regimen. Outcomes suggested a statistically significant higher OS in black vs white men with mCRPC who were enrolled in these clinical trials after adjusting for known prognostic factors.
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