Yu D, et al. - In this study with 1.6 million Americans, Europeans, and Asians, researchers assessed the associations of body mass index (BMI), waist circumference (WC), and waist-hip ratio (WHR) with lung cancer risk. Adjusting for potential confounders, Cox proportional hazard regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Adjusting for BMI, analyses for WC/WHR were carried out. They also assessed the joint impact of BMI and WC/WHR. Findings revealed an inverse BMI-lung cancer link, which was not completely attributed to smoking and reverse causation. In the detection of high-risk populations for lung cancer, central obesity, particularly concomitant with low BMI, may be helpful.