Gaba P, Serruys PW, Karmpaliotis D, et al. - Researchers assessed the results of outpatient percutaneous coronary intervention (PCI) in patients with unprotected left main coronary artery disease (LMCAD). A total of 1,905 patients with LMCAD and site-assessed low or intermediate SYNTAX scores, who were enrolled in the EXCEL trial, were randomly assigned to PCI with everolimus-eluting stents vs coronary artery bypass grafting. Major adverse cardiovascular events (MACE; the composite of death, stroke, or myocardial infarction) was assessed as the primary endpoint. Findings of the EXCEL trial revealed that among patients with LMCAD, outpatient PCI was not related to an excess early or late hazard of MACE, and it was also suggested that safely performing outpatient PCI may be possible in select patients with LMCAD.