Bordoni V, Poggi A, Zaffagnini S, et al. - A meta-analysis was performed to compare outpatient and inpatient total knee arthroplasty (TKA). Researchers conducted a systematic search of the literature in July 2020 on PubMed, Web of Science, Cochrane library, and on the grey literature databases. For a meta-analysis, the papers collected were applied to compare outpatient and inpatient TKA in terms of complication and readmission rates. They characterized the risk of bias and quality of evidence according to Cochrane guidelines. This research enrolled a sum of 212,632 individuals. Although there were no differences in the number of readmissions, this meta-analysis documented that outpatient TKA led to an elevated number of complications. Nevertheless, further high-level research is required to verify outcomes and indications for the outpatient approach, since the studies currently available have a moderate risk of bias and very low quality of evidence.