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Outpatient pulmonary rehabilitation for severe asthma with fixed airway obstruction: Comparison with COPD

Journal of Asthma Nov 06, 2019

Bellocq A, Gaspard W, Couffignal C, et al. - Given the benefit of exercise demonstrated in asthma, researchers investigated the role of pulmonary rehabilitation (PR) in people with severe asthma, especially with airway obstruction. As the activity limitation mechanisms differ in asthma and COPD, so they sought to assess the effect of a PR program not specific to asthma. They performed a comparison of the effect of an ambulatory PR program in nonsmoking patients with severe asthma and airway obstruction (FEV1/FVC ratio < 70% and FEV1 < 80% measured twice, not under an exacerbation) vs gender-, age-, FEV1-, and BMI-matched COPD controls. Inclusion of 29 patients, each with asthma and COPD, was performed. Outcomes support the feasibility and good-tolerability of outpatient PR among patients with severe asthma with fixed airway obstruction. A nondedicated program greatly improves Hospital Anxiety and Depression Scale (HAD) and St. George’s Respiratory Questionnaire (SGRQ) scores and constant work-rate sub-maximal cycling, with a similar amplitude as with COPD.
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