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Outcomes of reproduction following cesarean scar pregnancy treatment: A systematic review and meta-analysis

European Journal of Obstetrics & Gynecology and Reproductive Biology May 15, 2021

Wu J, Ye J, OuYang Z, et al. - In this study, the reproductive outcomes of women with a history of cesarean scar pregnancy (CSP) and the influence of various treatments on subsequent pregnancy outcomes were investigated. Researchers enrolled a total of 32 studies including 3,380 cases of CSP, of which 583 cases conceived again after treatment (including 292 cases of unexpected pregnancy), and finally 178 cases delivered successfully. Researchers carried out searches of PubMed, Embase, Medline, Cochrane Library, and ClinicalTrial.gov databases for studies with the outcomes of pregnancy after CSP treatment. After CSP, the outcomes of reproduction included intrauterine pregnancy, recurrent CSP (RCSP), and other sites of ectopic pregnancy. Although the risk of RCSP and spontaneous miscarriage is elevated, women with a history of CSP still have a high pregnancy rate. It is difficult to verify the effect of different treatments on subsequent pregnancy. If the resection and repair of cesarean scar can ameliorate reproductive outcomes needs to be further evaluated. There is a need for further large-scale prospective studies, even RCTs with long-term follow-up to expound on the outcomes of reproduction after CSP and the effect of different treatments on subsequent reproductive outcomes.

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