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Outcomes of pregnancies diagnosed with circumvallate placenta, and use of uterine artery pulsatility index and maternal serum alpha-fetoprotein for prediction of adverse outcomes

European Journal of Obstetrics & Gynecology and Reproductive Biology May 13, 2021

Celik OY, Obut M, Keles A, et al. - This study was undertaken to investigate the outcomes and predictive value of uterine artery pulsatility index (UtA-PI) and second-trimester maternal serum alpha-fetoprotein (MSAFP) for adverse obstetric outcomes in cases with morphologically confirmed circumvallate placenta by comparison with normal pregnancies. Researchers conducted a prospective study in a tertiary referral hospital between January 2017 and December 2019. They assessed 77 patients with a circumvallate placenta and 77 patients without any placental or feto-maternal diseases or abnormalities during the study period. The outcomes revealed that circumvallate placenta was correlated with a higher rate of intrauterine growth restriction (IUGR), preterm birth, and bleeding at the time of delivery. It has been considered that UtA-PI and MSAFP may be valuable as predictors of IUGR in patients with a circumvallate placenta.

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