Cepas-Guillén PL, Borrego-Rodriguez J, Flores-Umanzor E, et al. - Among nonagenarian patients presenting with ST-segment elevation myocardial infarction (STEMI), researchers undertook an investigation to evaluate the clinical presentation as well as outcomes. In addition, they compared patients managed with optimal medical treatment alone vs those treated with primary percutaneous coronary intervention (pPCI) in terms of in-hospital and 1-year clinical results. This study included 167 nonagenarian patients from 2 academic centers (mean age 91.9 ± 0.17 years; 60% females). They found lower mortality in the pPCI group vs in the medical treatment group. An increasingly common appearance of STEMI in nonagenarians was reported. In this high-risk cohort, the preferred strategy may be pPCI in the absence of a high grade of disability. The factors that may be associated with prognosis in these patients are hemodynamic compromise, the presence of complications associated with myocardial infarction, renal impairment, and early revascularization.