Morici N, et al. - Researchers conducted this retrospective cohort study to analyze the comparative description of the clinical characteristics and outcomes of elderly patients with the acute coronary syndrome (ACS) undergoing percutaneous coronary intervention during the index admission. The study sample consisted of patients enrolled in the Elderly ACS-2 multicenter randomized trial. Compared with those with non-ST-elevation ACS (NSTEACS), patients with ST-elevation myocardial infarction (STEMI) had more favorable baseline risk factors, fewer previous cardiovascular events, less severe coronary disease, and lower ejection. The risks of cardiovascular death, non-cardiovascular death, and stroke were significantly higher in the STEMI group after adjustment for sex, age, and previous myocardial infarction. Findings suggested that elderly STEMI patients have worse survival and a higher risk of stroke vs NSTEACS patients after percutaneous coronary intervention, despite more favorable baseline characteristics.