Oblizajek N, Takahashi N, Agayeva S, et al. - Researchers conducted this matched case-control study to test the effectiveness and safety of endoscopic intervention of pancreatic necrosis (PN) ≤ 4 weeks from disease onset. For this investigation, they retrospectively reviewed the records and imaging studies of all individuals undergoing early endoscopic intervention of PN between 2008 and 2018 at one referral center. Excluded were patients who had previous interventional treatment. They identified 19 patients with early intervention. Infection was the most common indication for intervention. According to findings, PN endoscopic intervention in the third and fourth weeks of illness seems effective and safe when a partial collection wall is present on cross-sectional imaging studies, with findings similar to those reported for walled-off necrosis intervention.