Lim PS, Tran S, Kroeze SGC, et al. - Researchers analyzed adolescents and young adults (AYAs) (15‐39 years) with brain/skull base tumors who were managed with pencil beam scanning proton therapy (PT), focusing on outcomes and late toxicity consequences in these groups of patients. They selected 176 AYAs treated curatively at the Paul Scherrer Institute, with a median age of 30 years (range 15‐39) and a median prescribed dose of 70.0 Gy (relative biological effectiveness) (range 50.4‐76.0). Experts found 24 (13.6%) local only failures and one (0.6%) central nervous system distant only failure, following a median observation span of 66 months (range 12‐236). The 6‐year local control, distant progression‐free survival, and overall survival were estimated to be 83.2%, 97.4%, and 90.2%, respectively. Overall, findings showed the effectiveness of PT, along with its reasonable late toxicity profile, in the treatment of patients with brain/skull base tumors in a AYA population. Although clinical outcomes were good, around one in four AYA survivors were unemployed post-treatment.