Clements AC, Dai X, Walsh JM, et al. - Since Prader‐Willi syndrome (PWS) raises the risk of obstructive sleep apnea (OSA) due to obesity, hypotonia, and abnormal ventilatory responses, researchers conducted this systematic review and meta‐analysis to assess post‐adenotonsillectomy complications, polysomnography changes, and quality of life in children with OSA and PWS. A total of 68 patients were included from eight studies with a moderate to high risk of bias. The most commonly reported complication was velopharyngeal insufficiency. Children with PWS who undergo adenotonsillectomy for OSA face a significant risk of postoperative complications, especially velopharyngeal insufficiency, which may necessitate additional interventions. Many patients had residual OSA despite improvements in polysomnography and quality of life. When families are exploring OSA care options, this information may be helpful.